With Nami on the verge of death, Luffy's crew abandons its voyage to Alabasta and goes looking for help. Their search leads them to frosty Drum Island, where the locals don't roll out the red carpet for pirates, and the only doctor in town lives atop a treacherous, snow-covered mountain.

As Luffy's crew prepares for a treacherous trek across the parched sands of Alabasta, they are joined by Chopper, the ship's new doctor. His healing powers are sure to come in handy with Crocodile and the assassins of Baroque Works plotting to take over the country by force. Meanwhile, Captain Smoker, a foe Luffy is powerless to defeat, continues to pursue the merry pirates to the far reaches of the globe.